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Contraindicated (one)pentobarbital will decrease the level or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers may end up in lessened serum concentrations and loss of antimalarial efficacypentobarbital will decrease the extent or effect of eltrombopag by a